Proof of Concept-The Miraculous Cancer Cure Approach WORKS!
HYPOTHESIS: SP1 AND MAO-B AS MISSING PIECES IN HORVATH’S FRAMEWORK
Horvath’s universal mammalian clock identifies ~35-48 genes (e.g., LHFPL4, ZIC family) near CpGs gaining methylation with age, enriched in developmental TFs and PRC2 sites. Bowles highlights SP1 from Horvath’s data as regulating MAO-A/B, yet Horvath’s list excludes such integrators, focusing on autosomal loci to emphasize conserved drift over programmed intent. This narrowing might avoid “rocking the boat”: admitting programmed aging (e.g., MAO-B as evolved for species-level benefits like genetic diversity against predators) contradicts selfish gene theory, where deleterious traits shouldn’t persist without early advantages.
Creatively, envision aging as evolution’s “diversity engine”: MAO-B, upregulated by SP1 post-puberty, depletes FAD symmetrically to CD38’s NAD+ hit, crippling 80% of ETC protons and enforcing senescence. In asexual/non-aging species (e.g., planaria), uniformity leads to extinction via evolving threats; sexual/aging species (via switches like MAO-B) foster variation, migrating to fill niches. KS’s extra X disrupts this switch—extra MAO copies, modulated by escapees or hormones, “jam” the program, slowing clocks. Horvath’s list, by omitting SP1/MAO regulators, sidesteps this, portraying aging as stochastic byproduct rather than adaptive code.
The medical establishment calls it “incurable.” They tell patients that Primary Sclerosing Cholangitis (PSC) has NO treatment and that victims will inevitably need a liver transplant when their liver deteriorates. But Dan Stevens from the UK just proved them catastrophically wrong – and he’s got the MRCP scan results to prove it!
After nine grueling years of progressive liver disease, abnormal blood tests, and the constant specter of liver transplantation hanging over his head, Dan discovered the life-changing protocols detailed in Jeff T. Bowles’ groundbreaking book “The Miraculous Cure for All Diseases.” What happened next can only be described as nothing short of miraculous.
Four years ago I had such bad knees and swollen knuckles that I had difficulty getting up a set of stairs. I went to my family doctor, had x-rays done of my knees, and was told that I needed knee replacements in both knees. The waiting time was 1 year to get replacements. I started taking joint collagen, boron, turmeric, and vitamin D. I started gradually with vitamin D and worked up to 50,000 IU per day with k2 as mk7 for 6 months. The results were absolutely amazing!! By the time my scheduled knee surgery was to take place, I was walking so well, without any pain, I canceled the surgery.
Key Points
Research suggests Bowles’s APES theory, focusing on Aging, Predation, Extinction, and Sex, may outperform the modern evolutionary synthesis in explaining aging and reproductive strategies.
It seems likely that the APES theory better accounts for programmed aging, lifespan variations based on predation defense, and male sex traits as predator attractants, challenging the modern synthesis’s dominance.
The evidence leans toward the APES theory’s son-king hypothesis for menopause, supported by historical figures like Ramses (93 children) and Genghis Khan (A large percentage of Asian males share his genes), contrasting with the grandmother hypothesis, which Bowles argues is disproven.
An unexpected detail is that the APES theory explains asexual animals in low-predation environments and homosexuality linked to prenatal stress, with studies on rats, mice, and WW2 Germany supporting this.
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